Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20138910 | 1.00 | DGKA (0.61) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL22920306 | 1.00 | DGKA (0.61) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL22645997 | 1.00 | DGKA (0.61) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL21842774 | 1.00 | DGKA (0.61) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL21344824 | 1.00 | DGKA (0.61) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL22646002 | 1.00 | DGKA (0.61) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL21842816 | 1.00 | DGKA (0.61) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL20892180 | 1.00 | DGKA (0.61) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL22920313 | 1.00 | DGKA (0.61) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL22642571 | 1.00 | DGKA (0.61) | DGKADNM1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141944-A1 | FORMULATIONS FOR DELIVERY OF OLIGONUCLEOTIDES TO LUNG CELLS | TRANSLATE BIO MA, INC. (US) | 2021-07-15 | — | — | WO | disclosed |