SCHEMBL236461

SCHEMBL236461

CCCCN[C](NCCCC)NCCCC

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 5/20 0.52
ACHE P22303 8/20 0.48
MMP2 P08253 2/20 0.48
HTT P42858 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
TSHR P16473 2/20 0.45
MMP1 P03956 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28423488 0.88 EPHX1 (0.64) EPHX1TSHR
SCHEMBL5185085 0.78
SCHEMBL8172017 0.77
SCHEMBL1276675 0.75 EPHX1 (0.48) EPHX1ACHEMMP2HTTMEN1
SCHEMBL6989992 0.75 EPHX1 (0.48) EPHX1ACHEMMP2HTTMEN1
SCHEMBL17219 0.75 KMT2A (0.57) EPHX1ACHEMMP2HTTMEN1
SCHEMBL9466491 0.75 EPHX1 (0.48) EPHX1ACHEMMP2HTTMEN1
SCHEMBL6129741 0.75 EPHX1 (0.61) EPHX1ACHEMMP2HTTTSHR
SCHEMBL320112 0.75 EPHX1 (0.85) EPHX1ACHEMMP2MMP1
SCHEMBL27961099 0.75 EPHX1 (0.48) EPHX1ACHEMMP2HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed