SCHEMBL6989992

SCHEMBL6989992

CCCCN[C](CC)NCCCC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 5/20 0.48
ACHE P22303 8/20 0.44
MMP2 P08253 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HTT P42858 2/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
TSHR P16473 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28445121 0.81 MMP1 (0.40) EPHX1MMP2MEN1KMT2A
SCHEMBL27961099 0.77 EPHX1 (0.48) EPHX1ACHEMMP2MEN1KMT2A
SCHEMBL236461 0.75 EPHX1 (0.52) EPHX1ACHEMMP2MEN1KMT2A
SCHEMBL5185085 0.73
SCHEMBL277343 0.72
SCHEMBL7796308 0.72
SCHEMBL2877507 0.72 EPHX1 (0.52) EPHX1TSHR
SCHEMBL10981737 0.72
SCHEMBL28879783 0.72
SCHEMBL9466491 0.71 EPHX1 (0.48) EPHX1ACHEMMP2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750618-B1 OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM UPJOHN CO (US) 2003-02-19 EP disclosed
US-5668286-A ANTIBIOTIC PHARMACIA & UPJOHN COMPANY (US) 1997-09-16 US disclosed
CN-1143961-A Oxazolidinone derivatives and pharmaceutical compositions containing them UPJOHN CO (US) 1997-02-26 CN disclosed
EP-0750618-A1 OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PHARMACIA & UPJOHN COMPANY (US) 1997-01-02 EP disclosed
WO-1995025106-A1 OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PHARMACIA & UPJOHN COMPANY (US) 1995-09-21 WO disclosed