SCHEMBL236464

SCHEMBL236464

CC(C)N[Si](NC1CCCCC1)(NC1CCCCC1)NC1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
HSD17B10 Q99714 1/20 0.38
EPHX1 P07099 5/20 0.33
ATM Q13315 1/20 0.32
SIGMAR1 Q99720 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
TSHR P16473 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234434 0.98 ALDH1A1 (0.33) ALDH1A1HSD17B10EPHX1GAAL3MBTL1
SCHEMBL234949 0.95 ALDH1A1 (0.38) ALDH1A1HSD17B10EPHX1ATMSIGMAR1
SCHEMBL232293 0.93 ALDH1A1 (0.33) ALDH1A1HSD17B10EPHX1GAAL3MBTL1
SCHEMBL888616 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10EPHX1SIGMAR1KDM4E
SCHEMBL888637 0.76 ALDH1A1 (0.44) ALDH1A1HSD17B10EPHX1SIGMAR1KDM4E
SCHEMBL233686 0.76 ALDH1A1 (0.33) ALDH1A1HSD17B10EPHX1ATM
SCHEMBL236287 0.76 ALDH1A1 (0.33) ALDH1A1HSD17B10EPHX1ATM
SCHEMBL234475 0.75 ALDH1A1 (0.41) ALDH1A1HSD17B10EPHX1SIGMAR1KDM4E
SCHEMBL236569 0.75 ALDH1A1 (0.41) ALDH1A1HSD17B10EPHX1SIGMAR1KDM4E
SCHEMBL236425 0.75 ALDH1A1 (0.41) ALDH1A1HSD17B10EPHX1SIGMAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed