Malonic Acid

Malonic Acid

SCHEMBL2364720

CCC(=O)O.O=C(O)CC(=O)O

nearest known ligand 0.77

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.77
LDHA P00338 1/20 0.69
SRR Q9GZT4 1/20 0.69
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
TDP1 Q9NUW8 4/20 0.44
ALDH1A1 P00352 3/20 0.44
AKR1B1 P15121 1/20 0.38
LMNA P02545 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
PPARG P37231 6/20 0.36
PPARD Q03181 6/20 0.36
PPARA Q07869 6/20 0.36
GPR84 Q9NQS5 5/20 0.36
HDAC11 Q96DB2 5/20 0.36
TSHR P16473 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL2037328 1.00 FFAR3 (0.77) FFAR3LDHASRRHDAC3HDAC1
Malonic Acid SCHEMBL28993583 0.88 LDHA (0.75) FFAR3LDHASRRHDAC3HDAC1
Propionic Acid SCHEMBL1331656 0.88
Propionic Acid SCHEMBL11661434 0.88 FFAR3 (1.00) FFAR3LDHASRRHDAC3HDAC1
Propionic Acid SCHEMBL7088331 0.88 FFAR3 (1.00) FFAR3LDHASRRHDAC3HDAC1
Propionic Acid SCHEMBL1332599 0.88
Propionic Acid SCHEMBL1331605 0.88
Propionic Acid SCHEMBL19409 0.88 FFAR3 (1.00) FFAR3LDHASRRHDAC3HDAC1
Propionic Acid SCHEMBL1462509 0.88 FFAR3 (1.00) FFAR3LDHASRRHDAC3HDAC1
Propionic Acid SCHEMBL290 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023092044-A2 PHENETHYLAMINE COMPOUNDS SALTS, POLYMORPHIC FORMS AND METHODS OF USE THEREOF TERRAN BIOSCIENCES, INC. (US) 2023-05-25 WO disclosed
EP-2259785-B1 FULLERENE THERAPIES FOR INFLAMMATION LUNA INNOVATIONS INC (US) 2015-12-23 EP disclosed
EP-2352759-A2 HUMAN CYTOMEGALOVIRUS NEUTRALIZING ANTIBODIES AND USE THEREOF Institute for Research in Biomedicine (CH) 2011-08-10 EP disclosed
EP-2259785-A2 FULLERENE THERAPIES FOR INFLAMMATION Luna Innovations Incorporated (US) 2010-12-15 EP disclosed
WO-2010007533-A2 HUMAN CYTOMEGALOVIRUS NEUTRALIZING ANTIBODIES AND USE THEREOF INSTITUTE FOR RESEARCH IN BIOMEDICINE (CH) 2010-01-21 WO disclosed
WO-2009114088-A2 FULLERENE THERAPIES FOR INFLAMMATION LUNA INNOVATIONS INCORPORATED (US) 2009-09-17 WO disclosed
WO-2009105723-A2 NOVEL METHODS FOR BONE TREATMENT BY MODULATING AN ARACHIDONIC ACID METABOLIC OR SIGNALING PATHWAY ACCELALOX, INC. (US) 2009-08-27 WO disclosed