Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 5/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30858557 | 0.79 | KMT2A (0.41) | ALDH1A1HTTMAPTCYP1A2CYP2C19 | |
| SCHEMBL31492406 | 0.79 | DAO (0.35) | ALDH1A1LMNATP53HTTPGR | |
| SCHEMBL4813479 | 0.76 | PGR (0.41) | ALDH1A1LMNATP53HTTPGR | |
| SCHEMBL4779068 | 0.74 | PGR (0.32) | ALDH1A1LMNATP53HTTPGR | |
| SCHEMBL16849905 | 0.73 | PDE7A (0.35) | ALDH1A1LMNATP53HTTMAPT | |
| SCHEMBL31492415 | 0.73 | PGR (0.33) | ALDH1A1LMNATP53HTTPGR | |
| SCHEMBL3522002 | 0.73 | PGR (0.67) | PGR | |
| SCHEMBL30224301 | 0.72 | PGR (0.32) | PGR | |
| SCHEMBL23994828 | 0.72 | PGR (0.32) | PGR | |
| SCHEMBL23647999 | 0.70 | PGR (0.34) | PGRAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |
| WO-2021144439-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2021-07-22 | — | — | WO | disclosed |
| WO-2021144439-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2021-07-22 | — | — | WO | disclosed |