Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364641 | 0.85 | KCNN4 (0.42) | MTNR1AMTNR1BCYP1A2CYP2D6KMT2A | |
| SCHEMBL2364655 | 0.78 | CYP1A2 (0.42) | MTNR1AMTNR1BCYP1A2CYP2D6KMT2A | |
| SCHEMBL82057 | 0.71 | MTNR1A (0.45) | MTNR1AMTNR1BCYP1A2CYP2D6MEN1 | |
| SCHEMBL3745853 | 0.71 | CYP2D6 (0.41) | MTNR1AMTNR1BCYP1A2CYP2D6MEN1 | |
| SCHEMBL11035564 | 0.69 | CYP1A2 (0.50) | CYP1A2CYP2D6MEN1KMT2AGAA | |
| SCHEMBL11384019 | 0.67 | MTNR1A (0.57) | MTNR1AMTNR1BCYP1A2MEN1KMT2A | |
| SCHEMBL27159381 | 0.67 | CYP1A2 (0.44) | CYP1A2CYP2D6MEN1KMT2AGAA | |
| SCHEMBL27159384 | 0.67 | CYP1A2 (0.44) | CYP1A2CYP2D6MEN1KMT2AGAA | |
| SCHEMBL15881583 | 0.67 | KCNN4 (0.44) | CYP1A2CYP2D6KMT2AALDH1A1MAPT | |
| SCHEMBL10741457 | 0.67 | KCNN4 (0.44) | CYP1A2CYP2D6KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |