Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB3 | P54753 | 6/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 5/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361837 | 0.73 | — | — | |
| SCHEMBL20299311 | 0.71 | SMPD3 (0.37) | IDO1LCK | |
| SCHEMBL4840455 | 0.67 | IDO1 (0.32) | IDO1 | |
| SCHEMBL4569210 | 0.67 | HSP90AA1 (0.36) | — | |
| SCHEMBL20029255 | 0.64 | CCNK (0.38) | IDO1 | |
| SCHEMBL21672742 | 0.63 | IDO1 (0.31) | IDO1TDO2 | |
| SCHEMBL30544213 | 0.61 | CYP19A1 (0.32) | IDO1TDO2 | |
| SCHEMBL6349183 | 0.60 | IDO1 (0.53) | IDO1TDO2 | |
| SCHEMBL30544222 | 0.60 | IDO1 (0.31) | IDO1 | |
| SCHEMBL3396471 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361919-A1 | Imidazo[1,5-b] pyridazin-amino-phosphorous ligands and their complex compounds | AIKAA-Chemicals GmbH (DE) | 2011-08-31 | — | — | EP | disclosed |