SCHEMBL3396471

SCHEMBL3396471

c1cnn2cncc2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8134374 0.70 ALOX15 (0.36)
SCHEMBL297724 0.70
SCHEMBL2693230 0.70
Hydrochloric Acid SCHEMBL28275439 0.70 ALOX15 (0.36)
SCHEMBL15830161 0.70
Ammonia Solution, Strong SCHEMBL5132265 0.68 MAP4K4 (0.38)
Iodide SCHEMBL29862219 0.68 MAP4K4 (0.38)
SCHEMBL858847 0.67
SCHEMBL31463743 0.67
SCHEMBL559642 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2099801-B1 IMIDAZOÝ1,5-B¨PYRIDAZINAMIDO LIGANDS AND THEIR COMPLEXES AIKAA CHEMICALS GMBH (DE) 2010-11-03 EP claimed
US-7306631-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-12-11 US claimed
EP-1732509-A1 KERATIN DYEING COMPOSITIONS BICYCLIC 5-6 HETEROAROMATIC DYEING COMPOUNDS WITH ONE RING NITROGEN JUNCTION The Procter and Gamble Company (US) 2006-12-20 EP claimed
WO-2005097052-A1 KERATIN DYEING COMPOSITIONS BICYCLIC 5-6 HETEROAROMATIC DYEING COMPOUNDS WITH ONE RING NITROGEN JUNCTION THE PROCTER & GAMBLE COMPANY (US) 2005-10-20 WO claimed
US-20050229333-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-20 US claimed
US-20260049093-A1 Bicyclic Ureas As Kinase Inhibitors INCYTE CORP (US) 2026-02-19 US disclosed
US-20260042781-A1 Bicyclic Ureas As Kinase Inhibitors INCYTE CORP (US) 2026-02-12 US disclosed
WO-2025044946-A1 COMPOUND ACTING AS MRGPRX2 ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF 武汉人福创新药物研发中心有限公司 2025-03-06 WO disclosed
US-12240820-B2 Barbituric acid derivatives, their preparation and use thereof as leukocyte transmigration inhibitors and for treating inflammatory diseases, autoimmune diseases and cancer BAR-ILAN UNIVERSITY (IL) 2025-03-04 US disclosed
CN-119504738-A Compounds as MRGPRX2 antagonists, methods of preparation and use thereof 武汉人福创新药物研发中心有限公司 2025-02-25 CN disclosed
EP-4267581-A4 SUBSTITUTED IMIDAZO[1,5-B]PYRIDAZINE COMPOUNDS AS KINASE INHIBITORS AND USE THEREOF Impact Therapeutics (Shanghai), Inc (CN) 2025-01-01 EP disclosed
US-20240228490-A1 HETEROCYCLIC DERIVATIVE INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) 2024-07-11 US disclosed
WO-2005097052-A1 KERATIN DYEING COMPOSITIONS BICYCLIC 5-6 HETEROAROMATIC DYEING COMPOUNDS WITH ONE RING NITROGEN JUNCTION THE PROCTER & GAMBLE COMPANY (US) 2005-10-20 WO disclosed
WO-2005080355-A1 IMIDAZO-PYRIDAZINES, TRIAZOLO-PYRIDAZINES AND RELATED BENZODIAZEPINE RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 2005-09-01 WO disclosed
US-20050020634-A1 Coumarin derivatives, process for their production and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-01-27 US disclosed
EP-1471064-A1 COUMARIN DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-10-27 EP disclosed
WO-2004074259-A1 ARYL ACID PYRIMIDINYL METHYL AMIDES, PYRIDAZINYL METHYL AMIDES AND RELATED COMPOUNDS NEUROGEN CORPORATION (US) 2004-09-02 WO disclosed
US-20040167122-A1 Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands WYETH 2004-08-26 US disclosed
US-20040167122-A1 Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands WYETH 2004-08-26 US disclosed
US-4690917-A Imidazopyridayine derivatives having antiviral activity GLAXO GROUP LIMITED (GB) 1987-09-01 US disclosed