SCHEMBL2365075

CC(C)=CCC/C(C)=C/CC/C(C)=C/CC[C@]1(C)CCc2cc(OC(=O)/C=C\C(=O)O)c(C)c(C)c2O1.CC(C)=CCC/C(C)=C/CC/C(C)=C/CC[C@]1(C)CCc2cc(OC(=O)/C=C\C(=O)O)cc(C)c2O1

nearest known ligand 0.61

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	PPARA	Q07869	4/20	0.61

▸	PPARG	P37231	4/20	0.61

▸	ALOX5	P09917	12/20	0.60

▸	NR1I2	O75469	2/20	0.55

▸	PTGES	O14684	2/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2365077	1.00	PPARA (0.61)	PPARAPPARGALOX5NR1I2PTGES
SCHEMBL2292165	0.94	ALOX5 (0.60)	PPARAPPARGALOX5NR1I2PTGES
SCHEMBL2292170	0.94	ALOX5 (0.60)	PPARAPPARGALOX5NR1I2PTGES
SCHEMBL2292160	0.94	ALOX5 (0.60)	PPARAPPARGALOX5NR1I2PTGES
SCHEMBL2290611	0.94	PPARA (0.68)	PPARAPPARGALOX5NR1I2PTGES
SCHEMBL2290615	0.94	PPARA (0.68)	PPARAPPARGALOX5NR1I2PTGES
SCHEMBL2290607	0.94	PPARA (0.68)	PPARAPPARGALOX5NR1I2PTGES
SCHEMBL9321468	0.84	ALOX5 (0.64)	PPARAPPARGALOX5NR1I2PTGES
SCHEMBL2292589	0.81	ALOX5 (0.56)	PPARAPPARGALOX5NR1I2PTGES
SCHEMBL2292581	0.81	ALOX5 (0.56)	PPARAPPARGALOX5NR1I2PTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2531028-B1	TOCOTRIENOL ESTERS	FIRST TECH INTERNAT LTD (CN)	2014-12-31	—	—	EP	disclosed
EP-2531028-A1	TOCOTRIENOL ESTERS	First Tech International Limited (CN)	2012-12-12	—	—	EP	disclosed
WO-2011097481-A1	TOCOTRIENOL ESTERS	FIRST TECH INTERNATIONAL LIMITED (CN)	2011-08-11	—	—	WO	disclosed