Edetic Acid

Edetic Acid

SCHEMBL2365124

O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O.O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O.O=C(O)c1ccc(CN2CCCNCCNCCCNCC2)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 14/20 0.59
MEN1 O00255 1/20 0.59
CHRM2 P08172 1/20 0.59
CHRM1 P11229 1/20 0.59
ADRA2C P18825 1/20 0.59
CCR2 P41597 1/20 0.59
CXCL12 P48061 1/20 0.59
BLM P54132 1/20 0.59
KMT2A Q03164 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
HRH3 Q9Y5N1 1/20 0.59
SIGMAR1 Q99720 2/20 0.43
HDAC1 Q13547 2/20 0.42
KDM5C P41229 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL898695 0.89 CXCR4 (0.74) CXCR4MEN1CHRM2CHRM1ADRA2C
Hydrochloric Acid SCHEMBL2489671 0.88 CXCR4 (0.75) CXCR4MEN1CHRM2CHRM1ADRA2C
Hydrochloric Acid SCHEMBL5962418 0.83 CXCR4 (0.66) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL10006951 0.83 CXCR4 (0.63) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL13995932 0.83 SIGMAR1 (0.61) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL1160126 0.81 SIGMAR1 (0.62) CXCR4MEN1CHRM2CHRM1ADRA2C
Hydrochloric Acid SCHEMBL28273325 0.80 SIGMAR1 (0.61) CXCR4MEN1CHRM2CHRM1ADRA2C
Hydrochloric Acid SCHEMBL10901935 0.80 SIGMAR1 (0.61) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL3894421 0.78 CXCR4 (0.72) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL5611617 0.77 CXCR4 (1.00) CXCR4MEN1CHRM2CHRM1ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011123525-A1 FORMING AN ARTIFICIAL CELL WITH CONTROLLED MEMBRANE COMPOSITION, ASYMMETRY AND CONTENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-10-06 WO disclosed
WO-2011103490-A2 INTEGRIN αVβ8 NEUTRALIZING ANTIBODY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-08-25 WO disclosed