Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.35 |
| ▸ | HK2 | P52789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315803 | 1.00 | PYGB (0.48) | PYGBGAAKDM4ELMNACYP2D6 | |
| SCHEMBL19757480 | 1.00 | PYGB (0.48) | PYGBGAAKDM4ELMNACYP2D6 | |
| SCHEMBL19757478 | 1.00 | PYGB (0.48) | PYGBGAAKDM4ELMNACYP2D6 | |
| SCHEMBL20045991 | 0.90 | PYGB (0.40) | PYGBGAAKDM4ELMNACYP2D6 | |
| SCHEMBL15142824 | 0.90 | PYGB (0.40) | PYGBGAAKDM4ELMNACYP2D6 | |
| SCHEMBL20045971 | 0.90 | PYGB (0.40) | PYGBGAAKDM4ELMNACYP2D6 | |
| SCHEMBL14200457 | 0.88 | PYGB (0.45) | PYGBGAAKDM4ELMNACYP2D6 | |
| SCHEMBL12767213 | 0.88 | PYGB (0.45) | PYGBGAAKDM4ELMNACYP2D6 | |
| SCHEMBL18391212 | 0.87 | PYGB (0.64) | PYGBGAAKDM4ELMNACYP2D6 | |
| SCHEMBL21137865 | 0.87 | PYGB (0.64) | PYGBGAAKDM4ELMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3851109-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | The Regents of the University of California (US) | 2021-07-21 | — | — | EP | disclosed |