Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.31 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.31 |
| ▸ | RPS17 | P08708 | 1/20 | 0.31 |
| ▸ | RPSA | P08865 | 1/20 | 0.31 |
| ▸ | RPS2 | P15880 | 1/20 | 0.31 |
| ▸ | RPL35A | P18077 | 1/20 | 0.31 |
| ▸ | RPL7 | P18124 | 1/20 | 0.31 |
| ▸ | RPL17 | P18621 | 1/20 | 0.31 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.31 |
| ▸ | RPS3 | P23396 | 1/20 | 0.31 |
| ▸ | RPS12 | P25398 | 1/20 | 0.31 |
| ▸ | RPL13 | P26373 | 1/20 | 0.31 |
| ▸ | RPL10 | P27635 | 1/20 | 0.31 |
| ▸ | RPL12 | P30050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365213 | 1.00 | LMNA (0.55) | LMNAMEN1CYP3A4KMT2ATSHR | |
| SCHEMBL651241 | 0.91 | LMNA (0.56) | LMNAMEN1CYP3A4KMT2ATSHR | |
| SCHEMBL650389 | 0.91 | LMNA (0.56) | LMNAMEN1CYP3A4KMT2ATSHR | |
| SCHEMBL652874 | 0.91 | LMNA (0.56) | LMNAMEN1CYP3A4KMT2ATSHR | |
| SCHEMBL650390 | 0.91 | LMNA (0.56) | LMNAMEN1CYP3A4KMT2ATSHR | |
| SCHEMBL649716 | 0.88 | LMNA (0.59) | LMNAMEN1CYP3A4KMT2ATSHR | |
| SCHEMBL649717 | 0.88 | LMNA (0.59) | LMNAMEN1CYP3A4KMT2ATSHR | |
| SCHEMBL649986 | 0.87 | LMNA (0.68) | LMNAMEN1CYP3A4KMT2ATSHR | |
| SCHEMBL650299 | 0.87 | LMNA (0.68) | LMNAMEN1CYP3A4KMT2ATSHR | |
| SCHEMBL652758 | 0.86 | LMNA (0.70) | LMNAMEN1CYP3A4KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966129-B1 | CARBONATES OF FENICOL ANTIBIOTICS | SCHERING PLOUGH LTD (CH) | 2011-08-17 | — | — | EP | claimed |