Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 6/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314346 | 0.86 | MAOB (0.45) | KDM1AMAOBMAOARCOR1KDM1B | |
| SCHEMBL2364189 | 0.86 | MAOB (0.45) | KDM1AMAOBMAOARCOR1KDM1B | |
| SCHEMBL13836670 | 0.72 | MAOB (0.46) | KDM1AMAOBMAOARCOR1KDM1B | |
| SCHEMBL19609726 | 0.70 | KDM1A (1.00) | KDM1AMAOBMAOARCOR1KDM1B | |
| SCHEMBL8144680 | 0.70 | KDM1A (1.00) | KDM1AMAOBMAOARCOR1KDM1B | |
| SCHEMBL15200694 | 0.70 | KDM1A (1.00) | KDM1AMAOBMAOARCOR1KDM1B | |
| SCHEMBL17984427 | 0.70 | KDM1A (1.00) | KDM1AMAOBMAOARCOR1KDM1B | |
| SCHEMBL1800003 | 0.70 | KDM1A (1.00) | KDM1AMAOBMAOARCOR1KDM1B | |
| SCHEMBL1835492 | 0.70 | KDM1A (1.00) | KDM1AMAOBMAOARCOR1KDM1B | |
| SCHEMBL18023261 | 0.70 | KDM1A (1.00) | KDM1AMAOBMAOARCOR1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092611-A1 | AMINOCYCLOHEXANES AND AMINOTETRAHYDROPYRANS AND RELATED COMPOUNDS AS GAMMA-SECRETASE MODULATORS | PFIZER INC. (US) | 2011-08-04 | — | — | WO | disclosed |