Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 11/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256266 | 0.90 | TGM2 (0.59) | TGM2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17524715 | 0.85 | TGM2 (0.54) | TGM2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15939027 | 0.82 | TGM2 (0.54) | TGM2HPGDGAAMAPTSMN1; SMN2 | |
| SCHEMBL15938644 | 0.82 | TGM2 (0.54) | TGM2HPGDGAAMAPTSMN1; SMN2 | |
| SCHEMBL31162390 | 0.81 | TGM2 (0.58) | TGM2CYP1A2CYP2C19GAAMAPT | |
| SCHEMBL31162339 | 0.81 | MEN1 (0.61) | TGM2HPGDMAPTSMN1; SMN2MEN1 | |
| SCHEMBL21894170 | 0.81 | TGM2 (0.58) | TGM2CYP1A2CYP2C19GAAMAPT | |
| SCHEMBL5078477 | 0.81 | MEN1 (0.61) | TGM2HPGDMAPTSMN1; SMN2MEN1 | |
| SCHEMBL17522185 | 0.81 | TGM2 (0.50) | TGM2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23652894 | 0.81 | TGM2 (0.53) | TGM2CYP2C19MAPK3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |