Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27219439 | 0.81 | ACP3 (0.44) | ACP3CNR2NFKB1LMNAGAA | |
| SCHEMBL10723272 | 0.79 | ACP3 (0.42) | ACP3CNR2NFKB1LMNAGAA | |
| SCHEMBL7570359 | 0.77 | ACP3 (0.50) | ACP3CNR2NFKB1LMNAGAA | |
| SCHEMBL9776265 | 0.77 | ACP3 (0.50) | ACP3CNR2NFKB1LMNAGAA | |
| SCHEMBL30903830 | 0.77 | ACP3 (0.50) | ACP3CNR2NFKB1LMNAGAA | |
| SCHEMBL21495118 | 0.77 | ACP3 (0.44) | ACP3CNR2NFKB1LMNAGAA | |
| SCHEMBL8427460 | 0.77 | ACP3 (0.44) | ACP3CNR2NFKB1CTSSP2RX7 | |
| SCHEMBL168980 | 0.77 | ACP3 (0.44) | ACP3CNR2NFKB1LMNAGAA | |
| SCHEMBL31378979 | 0.77 | ACP3 (0.44) | ACP3CNR2NFKB1LMNAGAA | |
| SCHEMBL31378987 | 0.77 | ACP3 (0.44) | ACP3CNR2NFKB1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352727-A1 | TRPV1 ANTAGONISTS | Abbott Laboratories (US) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010045402-A1 | TRPV1 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2010-04-22 | — | — | WO | disclosed |