Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643602 | 0.84 | CTSS (0.45) | ACP3P2RX7CTSSCTSK | |
| SCHEMBL6341623 | 0.82 | ALDH1A1 (0.39) | HSD11B1P2RX7TDP1ALDH1A1 | |
| SCHEMBL21331652 | 0.82 | P2RX7 (0.44) | ACP3HSD11B1P2RX7CNR2NFKB1 | |
| SCHEMBL29892221 | 0.82 | ALDH1A1 (0.39) | HSD11B1P2RX7TDP1ALDH1A1 | |
| SCHEMBL168980 | 0.81 | ACP3 (0.44) | ACP3HSD11B1P2RX7CTSSCNR2 | |
| SCHEMBL21495118 | 0.81 | ACP3 (0.44) | ACP3HSD11B1P2RX7CTSSCNR2 | |
| SCHEMBL14567995 | 0.81 | P2RX7 (0.43) | ACP3HSD11B1P2RX7CTSSCNR2 | |
| SCHEMBL1047625 | 0.78 | P2RX7 (0.52) | ACP3HSD11B1P2RX7CNR2TDP1 | |
| SCHEMBL84477 | 0.77 | P2RX7 (0.50) | ACP3HSD11B1P2RX7CNR2TDP1 | |
| SCHEMBL2365308 | 0.77 | ACP3 (0.47) | ACP3HSD11B1P2RX7CTSSCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101103026-A | Bicyclic heteroaryl derivatives for treating viruses | GENELABS INC (US) | 2008-01-09 | — | — | CN | disclosed |
| US-5973156-A | Piperidine and tetrahydropyridine derivatives | MERCK SHARP & DOME LTD. (GB) | 1999-10-26 | — | — | US | disclosed |
| EP-0861245-A1 | PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997019073-A1 | PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |