SCHEMBL23653151

SCHEMBL23653151

Cc1nnc(-n2cc(Cc3sc(C)nc3C)c3ccc(SNC4(C)CC4)cc32)s1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 20/20 0.69
ADPRS Q9NX46 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23652910 0.86 PARG (0.67) PARG
SCHEMBL23652892 0.84 PARG (0.68) PARG
SCHEMBL23652710 0.84 PARG (0.66) PARG
SCHEMBL17845494 0.82 PARG (1.00) PARGADPRS
SCHEMBL23996920 0.79 PARG (0.71) PARGADPRS
SCHEMBL23653161 0.77 PARG (0.67) PARG
SCHEMBL23653168 0.75 PARG (0.61) PARGADPRS
SCHEMBL23996919 0.75 PARG (0.40) PARGADPRS
SCHEMBL23652920 0.74 PARG (0.69) PARG
SCHEMBL23652724 0.74 PARG (0.70) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233845-B1 PARG INHIBITORY COMPOUNDS CANCER RESEARCH TECH LTD (GB) 2021-07-21 EP disclosed