SCHEMBL23653161

SCHEMBL23653161

CC(=O)c1cn(-c2nnc(C)s2)c2cc(SNC3(C)CC3)ccc12

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23652920 0.89 PARG (0.69) PARG
SCHEMBL23652724 0.87 PARG (0.70) PARG
SCHEMBL23996926 0.85 PARG (0.53) PARG
SCHEMBL17845560 0.80 PARG (1.00) PARG
SCHEMBL31122038 0.80 PARG (1.00) PARG
SCHEMBL23652710 0.80 PARG (0.66) PARG
SCHEMBL23652910 0.79 PARG (0.67) PARG
SCHEMBL23653151 0.77 PARG (0.69) PARG
SCHEMBL23652892 0.77 PARG (0.68) PARG
SCHEMBL23653163 0.77 PARG (0.70) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233845-B1 PARG INHIBITORY COMPOUNDS CANCER RESEARCH TECH LTD (GB) 2021-07-21 EP disclosed