Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | FGFR4 | P22455 | 14/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16071784 | 0.86 | FGFR1 (0.69) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL19363708 | 0.85 | FGFR1 (0.51) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16134009 | 0.83 | FGFR1 (0.69) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL15434021 | 0.82 | FGFR1 (0.74) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL18897273 | 0.77 | FGFR4 (0.73) | FGFR4 | |
| SCHEMBL23653057 | 0.77 | FGFR4 (0.54) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL22420093 | 0.76 | FGFR4 (0.74) | FGFR4FGFR2 | |
| SCHEMBL16071416 | 0.76 | FGFR4 (0.72) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL19068972 | 0.74 | FGFR4 (0.74) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL21860424 | 0.73 | FGFR4 (0.52) | EGFRFGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |