Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 19/20 | 0.74 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.54 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16072327 | 0.85 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24225084 | 0.77 | FGFR4 (0.73) | FGFR4 | |
| SCHEMBL15434021 | 0.76 | FGFR1 (0.74) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071492 | 0.76 | FGFR1 (0.82) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071412 | 0.76 | FGFR4 (0.89) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071681 | 0.75 | FGFR4 (0.72) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16134004 | 0.74 | FGFR4 (0.79) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16134031 | 0.74 | FGFR4 (0.78) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL23653226 | 0.74 | EGFR (0.51) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16133997 | 0.74 | FGFR4 (0.78) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695132-B2 | Heteroaryl compounds and uses thereof | CELGENE CAR LLC (BM) | 2017-07-04 | — | — | US | disclosed |