Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 17/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.54 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19363704 | 0.88 | FGFR4 (0.63) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL16071598 | 0.86 | FGFR1 (0.70) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071560 | 0.86 | FGFR4 (0.56) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL24224972 | 0.86 | FGFR4 (0.74) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071783 | 0.82 | FGFR4 (0.53) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL23653402 | 0.78 | FGFR4 (0.48) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL24690232 | 0.78 | FGFR4 (0.52) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL19069249 | 0.78 | FGFR4 (0.52) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL16071525 | 0.78 | FGFR4 (0.75) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071527 | 0.77 | FGFR4 (0.65) | FGFR4FGFR1FGFR2FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |