Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 15/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16071783 | 0.95 | FGFR4 (0.53) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL16071560 | 0.82 | FGFR4 (0.56) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL17522151 | 0.79 | FGFR4 (0.70) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL23653228 | 0.78 | FGFR4 (0.58) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL19363704 | 0.77 | FGFR4 (0.63) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL15434047 | 0.77 | FGFR1 (0.68) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL20733939 | 0.76 | FGFR4 (0.54) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL16071598 | 0.75 | FGFR1 (0.70) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL23653119 | 0.74 | FGFR4 (0.64) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL16071527 | 0.73 | FGFR4 (0.65) | FGFR4FGFR1FGFR2FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |