Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 15/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16134080 | 0.75 | FGFR4 (0.74) | FGFR4 | |
| SCHEMBL24690431 | 0.75 | FGFR4 (0.51) | FGFR4MAPK3PTK2 | |
| SCHEMBL21166439 | 0.74 | FGFR4 (0.46) | FGFR4MAPK3PTK2FGFR1FGFR2 | |
| SCHEMBL17974143 | 0.73 | FGFR4 (0.49) | FGFR4MAPK3FGFR1FGFR2FGFR3 | |
| SCHEMBL19801126 | 0.69 | FGFR4 (0.60) | FGFR4MAPK3FGFR1FGFR2FGFR3 | |
| SCHEMBL15946708 | 0.66 | CCNK (0.42) | MAPK3PTK2 | |
| SCHEMBL16137332 | 0.65 | LRRK2 (0.47) | MAPK3 | |
| SCHEMBL15434041 | 0.65 | MAPK3 (0.47) | FGFR4MAPK3PTK2FGFR1 | |
| SCHEMBL16134078 | 0.64 | SYK (0.44) | FGFR4MAPK3 | |
| SCHEMBL15948508 | 0.64 | MAPK3 (0.48) | MAPK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |