Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 11/20 | 0.51 |
| ▸ | MAPK3 | P27361 | 6/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690432 | 0.85 | FGFR4 (0.69) | FGFR4MAPK3 | |
| SCHEMBL16137332 | 0.81 | LRRK2 (0.47) | MAPK3SYKLRRK2 | |
| SCHEMBL16134078 | 0.80 | SYK (0.44) | FGFR4MAPK3SYKLRRK2 | |
| SCHEMBL16134080 | 0.78 | FGFR4 (0.74) | FGFR4 | |
| SCHEMBL16134079 | 0.77 | PLK1 (0.48) | MAPK3SYKLRRK2PTK2 | |
| SCHEMBL23653249 | 0.75 | FGFR4 (0.43) | FGFR4MAPK3PTK2 | |
| SCHEMBL17974143 | 0.72 | FGFR4 (0.49) | FGFR4MAPK3LRRK2 | |
| SCHEMBL15946708 | 0.71 | CCNK (0.42) | MAPK3SYKLRRK2PTK2 | |
| SCHEMBL21166439 | 0.71 | FGFR4 (0.46) | FGFR4MAPK3LRRK2PTK2 | |
| SCHEMBL16367921 | 0.71 | FGFR4 (0.75) | FGFR4MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332687-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | SANOFI (FR) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332687-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | ABCG2, CYP3A43, CYP3A5 | FGFR4 2623/4885MAPK3 4111/4885SYK 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.