SCHEMBL2365387

SCHEMBL2365387

CC1=C(C)C(C)C([Ti](C)(NC2CCCCCCCC2)[SiH2]c2ccccc2)=C1C

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
KMT2A Q03164 2/20 0.32
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALOX12 P18054 1/20 0.30
PKM P14618 1/20 0.30
EPHX1 P07099 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MEN1 O00255 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2365451 1.00 NPC1 (0.32) NPC1RAB9AKMT2AGAAL3MBTL1
SCHEMBL2365394 1.00 NPC1 (0.32) NPC1RAB9AKMT2AGAAL3MBTL1
SCHEMBL5822648 1.00 NPC1 (0.32) NPC1RAB9AKMT2AGAAL3MBTL1
SCHEMBL2365129 0.99 GAA (0.32) NPC1RAB9AKMT2AGAAL3MBTL1
Biphenyl SCHEMBL7648587 0.96 KMT2A (0.33) NPC1RAB9AKMT2AGAAKDM4E
Biphenyl SCHEMBL7650529 0.96 KMT2A (0.33) NPC1RAB9AKMT2AGAAKDM4E
Biphenyl SCHEMBL7650623 0.96 KMT2A (0.33) NPC1RAB9AKMT2AGAAKDM4E
Biphenyl SCHEMBL7653512 0.96 KMT2A (0.33) NPC1RAB9AKMT2AGAAKDM4E
Biphenyl SCHEMBL7653656 0.96 KMT2A (0.33) NPC1RAB9AKMT2AGAAKDM4E
Biphenyl SCHEMBL7649341 0.96 KMT2A (0.33) NPC1RAB9AKMT2AGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675877-B1 POLYMERIZATION MONITORING AND CONTROL USING IMPROVED LEADING INDICATORS UNIVATION TECH LLC (US) 2011-08-10 EP disclosed
EP-1732954-A2 POLYMERIZATION MONITORING AND METHOD OF SELECTING LEADING INDICATORS Univation Technologies LLC (US) 2006-12-20 EP disclosed
EP-1675877-A2 POLYMERIZATION MONITORING AND CONTROL USING IMPROVED LEADING INDICATORS Univation Technologies LLC (US) 2006-07-05 EP disclosed
WO-2005040227-A2 POLYMERIZATION MONITORING AND CONTROL USING IMPROVED LEADING INDICATORS UNIVATION TECHNOLOGIES, LLC (US) 2005-05-06 WO disclosed
WO-2005040226-A2 POLYMERIZATION MONITORING AND METHOD OF SELECTING LEADING INDICATORS UNIVATION TECHNOLOGIES, LLC (US) 2005-05-06 WO disclosed
US-6855784-B2 Synthesis of polymerization catalyst components UNIVATION TECHNOLOGIES, LLC (US) 2005-02-15 US disclosed