Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365451 | 1.00 | NPC1 (0.32) | NPC1RAB9AKMT2AGAAL3MBTL1 | |
| SCHEMBL2365394 | 1.00 | NPC1 (0.32) | NPC1RAB9AKMT2AGAAL3MBTL1 | |
| SCHEMBL2365387 | 1.00 | NPC1 (0.32) | NPC1RAB9AKMT2AGAAL3MBTL1 | |
| SCHEMBL2365129 | 0.99 | GAA (0.32) | NPC1RAB9AKMT2AGAAL3MBTL1 | |
| Biphenyl SCHEMBL7648587 | 0.96 | KMT2A (0.33) | NPC1RAB9AKMT2AGAAKDM4E | |
| Biphenyl SCHEMBL7650529 | 0.96 | KMT2A (0.33) | NPC1RAB9AKMT2AGAAKDM4E | |
| Biphenyl SCHEMBL7650623 | 0.96 | KMT2A (0.33) | NPC1RAB9AKMT2AGAAKDM4E | |
| Biphenyl SCHEMBL7653512 | 0.96 | KMT2A (0.33) | NPC1RAB9AKMT2AGAAKDM4E | |
| Biphenyl SCHEMBL7653656 | 0.96 | KMT2A (0.33) | NPC1RAB9AKMT2AGAAKDM4E | |
| Biphenyl SCHEMBL7649341 | 0.96 | KMT2A (0.33) | NPC1RAB9AKMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006096319-A2 | ZIEGLER-TYPE CATALYSTS HAVING INCREASED PRODUCTIVITY | UNIVATION TECHNOLOGIES, LLC (US) | 2006-09-14 | — | — | WO | disclosed |
| EP-1534758-A1 | GAS PHASE POLYMERIZATION PROCESS | Univation Technologies LLC (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004022605-A1 | GAS PHASE POLYMERIZATION PROCESS | UNIVATION TECHNOLOGIES, LLC (US) | 2004-03-18 | — | — | WO | disclosed |