Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.54 |
| ▸ | HMGCR | P04035 | 3/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365402 | 0.93 | NR3C2 (0.65) | NR3C2CHRNA7CA2CA1CA7 | |
| SCHEMBL2365487 | 0.89 | NR3C2 (0.67) | NR3C2CHRNA7CA2CA1CA4 | |
| SCHEMBL2548973 | 0.87 | NR3C2 (0.61) | NR3C2CA2CA1CA4CA7 | |
| SCHEMBL2545125 | 0.86 | NR3C2 (0.70) | NR3C2CA2CA1CA4CA7 | |
| SCHEMBL2365401 | 0.80 | NR3C2 (0.81) | NR3C2CA2CA1CA7CA9 | |
| SCHEMBL2359038 | 0.79 | NR3C2 (0.82) | NR3C2 | |
| SCHEMBL2548305 | 0.79 | NR3C2 (0.75) | NR3C2CA2CA1CA7CA9 | |
| SCHEMBL2548930 | 0.78 | NR3C2 (0.85) | NR3C2CA2CA1CA7CA9 | |
| SCHEMBL1381638 | 0.77 | NR3C2 (0.64) | NR3C2CA2CA1CA4CA7 | |
| SCHEMBL2357173 | 0.71 | NR3C2 (1.00) | NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349996-A1 | 1-PHENYLPYRROLE COMPOUNDS | Exelixis, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |