SCHEMBL23655124

SCHEMBL23655124

N#Cc1ccc(-c2ccc(-c3c(Cc4ccccc4)ccc4ccccc34)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 1/20 0.46
AR P10275 1/20 0.42
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
ANPEP P15144 1/20 0.40
MMP3 P08254 2/20 0.39
MAOB P27338 2/20 0.39
ABCB1 P08183 1/20 0.38
HPGD P15428 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.38
MAOA P21397 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24914351 0.89 CYP1A2 (0.43) CA1CA2GPR55MMP3GABRG2
SCHEMBL17360625 0.83 GPR55 (0.46) GPR55GABRA1GABRG2GABRB3
SCHEMBL23654686 0.76 MEN1 (0.44) GPR55MAOBHPGDMAOA
SCHEMBL20407236 0.75 AR (0.45) SLC22A12ARMMP3MAOBABCB1
SCHEMBL20405158 0.75 SLC22A12 (0.50) SLC22A12ARCA1CA2MMP3
SCHEMBL21399313 0.75 SLC22A12 (0.47) SLC22A12CYP11B2CA1CA2MMP3
SCHEMBL28573904 0.73 GPR55 (0.42) GPR55ANPEPGABRA1GABRG2GABRB3
SCHEMBL19435544 0.73 SLC22A12 (0.48) SLC22A12CA1CA2MMP3
SCHEMBL19435502 0.73 SLC22A12 (0.51) SLC22A12CA1CA2MMP3HPGD
SCHEMBL19562879 0.73 SLC22A12 (0.47) SLC22A12ARCYP11B1CYP11B2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3351537-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2023-01-18 EP disclosed
EP-3351536-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2021-07-21 EP disclosed