Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23655918 | 0.91 | — | — | |
| SCHEMBL21258705 | 0.88 | PTGIR (0.35) | PTGIRNR1H4FFAR4CCR5MMP2 | |
| SCHEMBL21258972 | 0.79 | CHRM4 (0.34) | NR1H4CCR5MMP2MCHR1 | |
| SCHEMBL21258940 | 0.79 | PTGIR (0.35) | PTGIR | |
| SCHEMBL21258676 | 0.78 | PTGIR (0.38) | PTGIR | |
| SCHEMBL21258877 | 0.77 | PTGIR (0.37) | PTGIRNR1H4DRD3 | |
| SCHEMBL21258828 | 0.77 | PTGIR (0.37) | PTGIR | |
| SCHEMBL21258693 | 0.76 | PTGDR (0.33) | PTGIRFFAR4 | |
| SCHEMBL21258660 | 0.75 | LTC4S (0.33) | PTGIRMCHR1 | |
| SCHEMBL23655443 | 0.74 | PTGIR (0.35) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3851106-A1 | MEDICAL USE OF PROSTACYCLIN RECEPTOR AGONIST | Chinese PLA General Hospital (CN) | 2021-07-21 | — | — | EP | disclosed |