Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129586 | 0.80 | ALDH1A1 (0.59) | ALDH1A1GAAHPGDMEN1KMT2A | |
| SCHEMBL31017587 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GAAHPGDMEN1KMT2A | |
| SCHEMBL8381400 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HPGDTHRBHSD17B10CYP3A4 | |
| SCHEMBL15476638 | 0.78 | CYP1A2 (0.56) | ALDH1A1HPGDTHRBHSD17B10CYP3A4 | |
| SCHEMBL9622094 | 0.75 | ALDH1A1 (0.47) | ALDH1A1GAAHPGDMEN1KMT2A | |
| Pyrene SCHEMBL28151585 | 0.73 | CYP1A2 (0.53) | ALDH1A1GAAHPGDMEN1KMT2A | |
| SCHEMBL29831525 | 0.73 | CYP1A2 (0.53) | ALDH1A1GAAHPGDMEN1KMT2A | |
| SCHEMBL1229467 | 0.73 | CYP1A2 (0.53) | ALDH1A1GAAHPGDMEN1KMT2A | |
| SCHEMBL28390349 | 0.73 | TRPM4 (0.42) | ALDH1A1GAAHPGDMEN1KMT2A | |
| SCHEMBL2047161 | 0.73 | CYP1A2 (0.57) | ALDH1A1GAAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2363133-A1 | Composition comprising DNA fragments and medical and cosmetic uses thereof | Trustees of Boston University (US) | 2011-09-07 | — | — | EP | disclosed |
| US-7094766-B1 | Use of locally applied DNA fragments | TRUSTEES OF BOSTON UNIVERSITY (US) | 2006-08-22 | — | — | US | disclosed |
| EP-1274410-A2 | USE OF LOCALLY APPLIED DNA FRAGMENTS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001074342-A2 | USE OF LOCALLY APPLIED DNA FRAGMENTS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2001-10-11 | — | — | WO | disclosed |
| US-6147056-A | THERAPY FOR PSORIASIS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2000-11-14 | — | — | US | disclosed |
| US-5525482-A | EXPOSING HUMAN TEST CELLS, TRANSFORMED TO EXPRESSCYTOCHROME P450 ENZYMES, TO TOXIC MATERIALS; DETECTING GENE DAMAGE | WAYNE STATE UNIVERSITY (US) | 1996-06-11 | — | — | US | disclosed |
| EP-0297547-A2 | Use of hydrolyzable tannins for treatement and prophylaxis of AIDS | LEAD CHEMICAL COMPANY LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |
| EP-0062237-A1 | Process for the determination of the carcinogenicity of chemical or physical agents | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 1982-10-13 | — | — | EP | disclosed |