SCHEMBL2365679

SCHEMBL2365679

O=C(O)c1cccc(S(=O)(=O)O)c1.[NaH].[NaH]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.61
FYN P06241 1/20 0.61
MAPT P10636 1/20 0.60
IL1RN P18510 1/20 0.60
F2 P00734 3/20 0.57
PRSS1 P07477 3/20 0.57
PRSS2 P07478 3/20 0.57
PRSS3 P35030 3/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CYP2C19 P33261 1/20 0.54
APEX1 P27695 1/20 0.54
AKR1C3 P42330 4/20 0.53
ALDH1A1 P00352 2/20 0.53
AKR1C1 Q04828 2/20 0.53
TSHR P16473 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MEP1B Q16820 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39402 1.00 LCK (0.61) LCKFYNMAPTIL1RNF2
SCHEMBL11174349 0.98 LCK (0.63) LCKFYNMAPTIL1RNF2
SCHEMBL981408 0.98 LCK (0.63) LCKFYNMAPTIL1RNF2
SCHEMBL31042233 0.98 LCK (0.63) LCKFYNMAPTIL1RNF2
SCHEMBL29812595 0.98 LCK (0.63) LCKFYNMAPTIL1RNF2
SCHEMBL135795 0.98 LCK (0.63) LCKFYNMAPTIL1RNF2
Hydrochloric Acid SCHEMBL10586127 0.96 LCK (0.61) LCKFYNMAPTIL1RNF2
SCHEMBL20584481 0.96 LCK (0.61) LCKFYNMAPTIL1RNF2
Hydrochloric Acid SCHEMBL11742111 0.96 LCK (0.61) LCKFYNMAPTIL1RNF2
Ammonia Solution, Strong SCHEMBL28449700 0.96 LCK (0.61) LCKFYNMAPTIL1RNF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109137007-B Environmentally friendly nickel electroplating compositions and methods 罗门哈斯电子材料有限责任公司 2020-07-07 CN disclosed
EP-3431634-A1 ENVIRONMENTALLY FRIENDLY NICKEL ELECTROPLATING COMPOSITIONS AND METHODS Rohm and Haas Electronic Materials LLC (US) 2019-01-23 EP disclosed
US-20180363157-A1 ENVIRONMENTALLY FRIENDLY NICKEL ELECTROPLATING COMPOSITIONS AND METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-12-20 US disclosed
US-20150174171-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND ALLEVIATION OF BONE AND CARTILAGE DISEASES OR INJURIES AND HAIR LOSS PAK JAE WOO (KR) 2015-06-25 US disclosed
US-20150174170-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND ALLEVIATION OF BONE AND CARTILAGE DISEASES OR INJURIES AND HAIR LOSS PAK JAE WOO (KR) 2015-06-25 US disclosed
US-20140186320-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT, PREVENTION, AND ALLEVIATION OF BONE AND CARTILAGE DISEASES OR INJURIES AND HAIR LOSS PAK JAE WOO (KR) 2014-07-03 US disclosed
US-8658012-B2 Biosensor for electrochemical measurement of 1,5-anhydroglucitol, and measuring method and measuring kit using the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-02-25 US disclosed
US-20120171179-A1 APPARATUS, SYSTEM, AND METHOD FOR COMPOSITIONS AND METHODS FOR TREATING, PREVENTING, OR ALLEVIATING BONE OR CARTILAGE DISEASES PAK JAEWOO (KR) 2012-07-05 US disclosed
US-20120171169-A1 COMPOSITIONS AND METHODS FOR TREATING, PREVENTING, OR ALLEVIATING BONE OR CARTILAGE DISEASES PAK JAEWOO (KR) 2012-07-05 US disclosed
US-20120171182-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT, PREVENTION, AND ALLEVIATION OF BONE AND CARTILAGE DISEASES OR INJURIES AND HAIR LOSS PAK JAE WOO (KR) 2012-07-05 US disclosed
EP-2365326-A1 BIOSENSOR FOR ELECTROCHEMICAL MEASUREMENT OF 1,5-ANHYDROGLUCITOL, AND MEASURING METHOD AND MEASURING KIT USING THE SAME Nippon Kayaku Kabushiki Kaisha (JP) 2011-09-14 EP disclosed
US-20050277624-A1 Use of corticosteroids alone or in conjunction with nutritional therapy to reduce stress in animals COOK NIGEL 2005-12-15 US disclosed
EP-1357916-A2 TWO-COMPONENT ANTI-EMETIC COMPOSITION COMPRISING DEXAMETHASONE AND METOCLOPRAMIDE Odyssey Pharmaceuticals LLC (US) 2003-11-05 EP disclosed
US-6544550-B1 For therpay and prophylaxis of nausea and vomiting GLAXO GROUP LIMITED (GB) 2003-04-08 US disclosed
US-20020055495-A1 Two-component anti-emetic composition ODYSSEY PHARMACEUTICALS, LLC 2002-05-09 US disclosed
WO-2002020001-A2 TWO-COMPONENT ANTI-EMETIC COMPOSITION COMPRISING DEXAMETHASONE AND METOCLOPRAMIDE ODYSSEY PHARMACEUTICALS LLC (US) 2002-03-14 WO disclosed
US-5929059-A Pharmaceutical compositions containing granisetron and dexamethasone SMITHKLINE BEECHAM P.L.C. (GB) 1999-07-27 US disclosed
US-5482716-A RELIEF OF NAUSEA AND VOMITING GLAXO GROUP LIMITED (GB) 1996-01-09 US disclosed
EP-0567498-A1 PHARMACEUTICAL COMPOSITION CONTAINING GRANISETRON AND DEXAMETHASONE SMITHKLINE BEECHAM PLC (GB) 1993-11-03 EP disclosed
WO-1992012716-A1 PHARMACEUTICAL COMPOSITION CONTAINING GRANISETRON AND DEXAMETHASONE SMITHKLINE BEECHAM P.L.C. (GB) 1992-08-06 WO disclosed