SCHEMBL981408

SCHEMBL981408

O=C(O)c1cccc(S(=O)(=O)O)c1.[Na]

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.63
FYN P06241 1/20 0.63
MAPT P10636 1/20 0.62
IL1RN P18510 1/20 0.62
F2 P00734 3/20 0.59
PRSS1 P07477 3/20 0.59
PRSS2 P07478 3/20 0.59
PRSS3 P35030 3/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CYP2C19 P33261 1/20 0.56
APEX1 P27695 1/20 0.55
AKR1C3 P42330 4/20 0.54
ALDH1A1 P00352 2/20 0.54
AKR1C1 Q04828 2/20 0.54
TSHR P16473 3/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
HSD17B10 Q99714 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
MEP1B Q16820 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29812595 1.00 LCK (0.63) LCKFYNMAPTIL1RNF2
SCHEMBL31042233 1.00 LCK (0.63) LCKFYNMAPTIL1RNF2
SCHEMBL11174349 1.00 LCK (0.63) LCKFYNMAPTIL1RNF2
SCHEMBL135795 1.00 LCK (0.63) LCKFYNMAPTIL1RNF2
SCHEMBL2365679 0.98 LCK (0.61) LCKFYNMAPTIL1RNF2
SCHEMBL38172 0.98 LCK (0.61) LCKFYNMAPTIL1RNF2
SCHEMBL20584481 0.98 LCK (0.61) LCKFYNMAPTIL1RNF2
Ammonia Solution, Strong SCHEMBL28449700 0.98 LCK (0.61) LCKFYNMAPTIL1RNF2
Hydrochloric Acid SCHEMBL11742111 0.98 LCK (0.61) LCKFYNMAPTIL1RNF2
Hydrochloric Acid SCHEMBL10586127 0.98 LCK (0.61) LCKFYNMAPTIL1RNF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026080-A1 METHOD FOR PRODUCING NYLON ALADDIN MANUFACTURING CORPORATION 2024-01-25 US claimed
WO-2024018319-A1 METHOD FOR PRODUCING NYLON ALADDIN MANUFACTURING CORPORATION (US) 2024-01-25 WO claimed
CN-115957322-A Novel immunostimulating nano-drug and application thereof in treatment of melanoma 中南大学湘雅医院 2023-04-14 CN claimed
CN-115381943-A Construction method and application of Apt @ SCH @ BPs of black phosphorus nano-medicament 中南大学湘雅医院 2022-11-25 CN claimed
EP-3222647-B1 POLYESTER, METHOD FOR THEIR PREPARATION AND THEIR USE WEYLCHEM WIESBADEN GMBH (DE) 2018-10-17 EP claimed
US-20170275420-A1 Polyesters, Manufacturing Process Thereof and Their Use WEYLCHEM WIESBADEN GMBH (DE) 2017-09-28 US claimed
US-7875694-B2 reacting a sulfobenzoic acid cyclic anhydride or sulfobenzoic acid sodium salt with amine functional siloxane; emulsion; useful in a variety of personal, household, healthcare formulations, as well as fabric and textile treatments; produced by a safer route DOW CORNING CORPORATION (US) 2011-01-25 US claimed
US-20090043069-A1 ACTIVATED ESTERS FOR SYNTHESIS OF SULFONATED TELECHELIC POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2009-02-12 US claimed
WO-2009020967-A1 ACTIVATED ESTERS FOR SYNTHESIS OF SULFONATED TELECHELIC POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-02-12 WO claimed
EP-1824905-B1 SULFONATE FUNCTIONAL ORGANOPOLYSILOXANES DOW CORNING (US) 2008-11-26 EP claimed
US-20070299140-A1 reacting a sulfobenzoic acid cyclic anhydride or sulfobenzoic acid sodium salt with amine functional siloxane; emulsion; useful in a variety of personal, household, healthcare formulations, as well as fabric and textile treatments; produced by a safer route KENNAN JOHN J 2007-12-27 US claimed
EP-1824905-A2 SULFONATE FUNCTIONAL ORGANOPOLYSILOXANES Dow Corning Corporation (US) 2007-08-29 EP claimed
WO-2006065467-A2 SULFONATE FUNCTIONAL ORGANOPOLYSILOXANES DOW CORNING CORPORATION (US) 2006-06-22 WO claimed
EP-0804203-B1 RECTAL FLUNISOLIDE COMPOSITIONS FOR TREATING INFLAMMATORY INTESTINAL DISORDERS VALEAS SPA (IT) 2000-03-22 EP claimed
US-5721228-A ADMINISTERING TOPICALLY AN EFFECTIVE AMOUNT OF FLUNISOLIDE OR A FLUNISOLIDE ESTER VALEAS S.P.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) 1998-02-24 US claimed
EP-0804203-A1 RECTAL FLUNISOLIDE COMPOSITIONS FOR TREATING INFLAMMATORY INTESTINAL DISORDERS VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) 1997-11-05 EP claimed
WO-1994012187-A1 RECTAL FLUNISOLIDE COMPOSITIONS FOR TREATING INFLAMMATORY INTESTINAL DISORDERS VALEAS S.P.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) 1994-06-09 WO claimed
JP-62021816-A None JP disclosed
EP-0026709-A2 Poly(alkylene oxide)composition containing a nitro-substituted aromatic compound UNION CARBIDE CORPORATION (US) 1981-04-08 EP disclosed
US-4000094-A FREE-FLOWING BUILT DETERGENTS THE PROCTER & GAMBLE COMPANY (US) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299140-A1 reacting a sulfobenzoic acid cyclic anhydride or sulfobenzoic acid sodium salt with amine functional siloxane; emulsion; useful in a variety of personal, household, healthcare formulations, as well as fabric and textile treatments; produced by a safer route STS, USP21, SCLY LCK 58/4885FYN 172/4885MAPT 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.