Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29771028 | 1.00 | PTPN11 (0.43) | PTPN11RET | |
| SCHEMBL22389873 | 0.93 | PTPN11 (0.51) | PTPN11 | |
| SCHEMBL29771167 | 0.93 | PTPN11 (0.51) | PTPN11 | |
| SCHEMBL31318780 | 0.85 | PTPN11 (0.52) | PTPN11 | |
| SCHEMBL22389872 | 0.85 | PTPN11 (0.52) | PTPN11 | |
| SCHEMBL23657273 | 0.83 | PTPN11 (0.49) | PTPN11 | |
| SCHEMBL29770937 | 0.83 | PTPN11 (0.49) | PTPN11 | |
| SCHEMBL23647631 | 0.83 | PTPN11 (0.56) | PTPN11 | |
| SCHEMBL23647634 | 0.82 | PTPN11 (0.46) | PTPN11 | |
| SCHEMBL28779225 | 0.81 | PTPN11 (0.50) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761394-B | Pyridine or pyrimidine derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115916765-A | Pyridine or pyrimidine derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114761394-A | Pyridine or pyrimidine derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| WO-2022007869-A1 | PYRIDINE OR PYRIMIDINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2022-01-13 | — | — | WO | disclosed |
| WO-2021143823-A1 | PYRIDINE OR PYRIMIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2021-07-22 | — | — | WO | disclosed |