Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29770937 | 1.00 | PTPN11 (0.49) | PTPN11 | |
| SCHEMBL29771167 | 0.90 | PTPN11 (0.51) | PTPN11 | |
| SCHEMBL22389873 | 0.90 | PTPN11 (0.51) | PTPN11 | |
| SCHEMBL21399418 | 0.87 | PTPN11 (0.53) | PTPN11 | |
| SCHEMBL29177470 | 0.86 | RET (0.41) | PTPN11 | |
| SCHEMBL28779242 | 0.84 | PTPN11 (0.57) | PTPN11 | |
| SCHEMBL21388789 | 0.83 | PTPN11 (0.56) | PTPN11 | |
| SCHEMBL29771083 | 0.83 | DRD2 (0.47) | PTPN11 | |
| SCHEMBL23647650 | 0.83 | DRD2 (0.47) | PTPN11 | |
| SCHEMBL23657157 | 0.83 | PTPN11 (0.43) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761394-B | Pyridine or pyrimidine derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115916765-A | Pyridine or pyrimidine derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114761394-A | Pyridine or pyrimidine derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| WO-2022007869-A1 | PYRIDINE OR PYRIMIDINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2022-01-13 | — | — | WO | disclosed |
| WO-2021143823-A1 | PYRIDINE OR PYRIMIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2021-07-22 | — | — | WO | disclosed |