Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912821 | 0.89 | MAPT (0.66) | MAPTNPSR1PKMALDH1A1GAA | |
| SCHEMBL25497888 | 0.83 | MAPT (0.51) | MAPTNPSR1PKMHSD17B10ALDH1A1 | |
| SCHEMBL25493045 | 0.81 | MAPT (0.50) | MAPTNPSR1PKMHSD17B10ALDH1A1 | |
| SCHEMBL9324883 | 0.77 | MAPT (0.51) | MAPTNPSR1PKMKMT2AMEN1 | |
| SCHEMBL15722731 | 0.76 | MAPT (0.47) | MAPTNPSR1PKMALDH1A1NPC1 | |
| SCHEMBL15722788 | 0.76 | MAPT (0.47) | MAPTNPSR1PKMALDH1A1NPC1 | |
| SCHEMBL15722787 | 0.76 | MAPT (0.47) | MAPTNPSR1PKMALDH1A1NPC1 | |
| SCHEMBL15722749 | 0.76 | MAPT (0.47) | MAPTNPSR1PKMALDH1A1NPC1 | |
| SCHEMBL13202774 | 0.75 | MAPT (0.46) | MAPTNPSR1PKMSMN1; SMN2KMT2A | |
| SCHEMBL23657200 | 0.73 | MEN1 (0.42) | MAPTNPSR1HSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |