SCHEMBL9324883

SCHEMBL9324883

COCn1cnc(Cl)c1Cl

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.51
NPSR1 Q6W5P4 1/20 0.46
POLB P06746 1/20 0.41
PKM P14618 1/20 0.40
CTSK P43235 2/20 0.36
MKNK1 Q9BUB5 1/20 0.32
MKNK2 Q9HBH9 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1912821 0.80 MAPT (0.66) MAPTNPSR1POLBPKMMEN1
SCHEMBL31332999 0.79 MAPT (0.37) MAPTNPSR1
SCHEMBL31332965 0.77 MAPT (0.36) MAPTNPSR1POLB
SCHEMBL9323973 0.74 MAPT (0.35) MAPTNPSR1
SCHEMBL9265326 0.73
SCHEMBL8957634 0.71
SCHEMBL13273348 0.71
SCHEMBL11723304 0.71 FDPS (0.51)
SCHEMBL18832304 0.70 P2RX7 (0.48)
SCHEMBL9428057 0.69 NPSR1 (0.51) MAPTNPSR1POLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365030-B1 Imidazole compound and process for preparing the same ISHIHARA SANGYO KAISHA (JP) 1994-01-26 EP disclosed
US-5023336-A Fungicides, biocides ISHIHARA SANGYO KAISHA LTD. (JP) 1991-06-11 US disclosed
EP-0365030-A1 Imidazole compound and process for preparing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1990-04-25 EP disclosed