⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365761 | 1.00 | — | — | |
| SCHEMBL2846867 | 1.00 | — | — | |
| SCHEMBL5149630 | 0.83 | — | — | |
| SCHEMBL16043519 | 0.83 | — | — | |
| SCHEMBL20026541 | 0.79 | — | — | |
| SCHEMBL15443713 | 0.79 | — | — | |
| SCHEMBL8907228 | 0.77 | — | — | |
| SCHEMBL18361687 | 0.77 | — | — | |
| SCHEMBL16054883 | 0.77 | — | — | |
| SCHEMBL20365021 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751355-A | Prostaglandin chiral intermediate and synthesis process thereof | 深圳格林凯特医药技术有限公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024040267-A2 | DIRECT SYNTHESIS OF N-(3-SUBSTITUTED-CHROMAN-4-YL)-7H- PYRROLO[2,3-D]PYRIMIDIN-4-AMINES AND DERIVATIVES THEREOF | MITOKININ, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| CN-112004790-A | Novel indoleamine 2, 3-dioxygenase inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-110357813-A | A kind of new indole amine 2,3- dioxygenase inhibitor and its preparation method and application | 信达生物制药(苏州)有限公司 | 2019-10-22 | — | — | CN | disclosed |
| WO-2019196780-A1 | NOVEL INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 信达生物制药(苏州)有限公司 | 2019-10-17 | — | — | WO | disclosed |
| EP-2364975-B1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-8354401-B2 | Oxazolidinone amide aromatic compounds for supressing MMP-9 production | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20110263571-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
| EP-2364975-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-1937688-B1 | IMIDAZO BENZODIAZEPINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-08-11 | — | — | EP | disclosed |
| US-20100168426-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES | IPSEN/S.C.R.A.S. (ANDRE BOURGOUIN) (FR) | 2010-07-01 | — | — | US | disclosed |
| US-7705155-B2 | Processes for the production of useful intermediates | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2010-04-27 | — | — | US | disclosed |
| US-20090247563-A9 | Novel Processes for the Production of Useful Intermediates | IPSEN/S.C.R.A.S. (ANDRE BOURGOUIN) (FR) | 2009-10-01 | — | — | US | disclosed |
| US-7507729-B2 | for the treatment of cognitive disorders, anxiety, schizophrenia, and Alzheimer's disease; ligands; GABA A alpha 5 receptor inhibitors; 3-bromo-10-chloro-6-(2-oxo-pyrrolidin-1-ylmethyl)-9H-imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepine | HOFFMANN-LA ROCHE INC. (US) | 2009-03-24 | — | — | US | disclosed |
| US-20070167475-A1 | Novel Processes for the Production of Useful Intermediates | IPSEN/S.C.R.A.S. (ANDRE BOURGOUIN) (FR) | 2007-07-19 | — | — | US | disclosed |
| US-7241796-B2 | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease | VERTEX PHARMACEUTICALS INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-20070082890-A1 | Substituted imidazo-[1,5-a][1,2,4]triazolo[1,5-d][1,4] benzodiazepine derivatives | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2007-04-12 | — | — | US | disclosed |
| EP-0728736-B1 | Process for the preparation of optically active tert-leucinol and use thereof | DEGUSSA (DE) | 1998-08-19 | — | — | EP | disclosed |
| US-5723667-A | Method of producing optically active tert-leucinol and its use | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0728736-A1 | Process for the preparation of optically active tert-leucinol and use thereof | Degussa Aktiengesellschaft (DE) | 1996-08-28 | — | — | EP | disclosed |