⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18361687 | 1.00 | — | — | |
| SCHEMBL16043519 | 0.83 | — | — | |
| SCHEMBL2365761 | 0.77 | — | — | |
| SCHEMBL2365758 | 0.77 | — | — | |
| SCHEMBL2846867 | 0.77 | — | — | |
| SCHEMBL5149630 | 0.74 | — | — | |
| SCHEMBL15443713 | 0.71 | — | — | |
| SCHEMBL20026541 | 0.71 | — | — | |
| SCHEMBL31627042 | 0.70 | GAA (0.30) | — | |
| SCHEMBL16054883 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158412-A1 | UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF | FAXIAN THERAPEUTICS, LLC | 2024-05-16 | — | — | US | disclosed |
| EP-4288442-A1 | UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF | Faxian Therapeutics, LLC (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022170198-A1 | UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF | FAXIAN THERAPEUTICS, LLC (US) | 2022-08-11 | — | — | WO | disclosed |
| CN-111848643-A | Benzoxazepine compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-107995911-B | Benzoxazepine compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2020-08-04 | — | — | CN | disclosed |
| EP-3317283-B1 | BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2019-04-03 | — | — | EP | disclosed |
| US-9643980-B2 | Benzoxazepin oxazolidinone compounds and methods of use | GENENTECH, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-5683989-A | TREATMENT OF CARDIOVASCULAR AND NERVOUS SYSTEM DISORDERS | NOVO NORDISK A/S (DK) | 1997-11-04 | — | — | US | disclosed |
| US-5484774-A | 2, N6 -disubstituted adenosines, tri-O-ester derivatives and their pharmaceutical compositions to treat ischemias | NOVO NORDISK A/S (DK) | 1996-01-16 | — | — | US | disclosed |
| EP-0675896-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994014832-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-07-07 | — | — | WO | disclosed |