Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.31 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23648003 | 0.81 | MOGAT2 (0.34) | MOGAT2 | |
| SCHEMBL23648098 | 0.79 | — | — | |
| SCHEMBL21624172 | 0.73 | AKR1B1 (0.43) | — | |
| SCHEMBL21624113 | 0.70 | MOGAT2 (0.40) | MOGAT2 | |
| SCHEMBL21636537 | 0.68 | MOGAT2 (0.46) | MOGAT2 | |
| SCHEMBL19366887 | 0.66 | — | — | |
| SCHEMBL3595402 | 0.62 | BRD4 (0.37) | MGAT2 | |
| SCHEMBL23648086 | 0.61 | — | — | |
| SCHEMBL21624341 | 0.61 | MOGAT2 (0.38) | MOGAT2 | |
| SCHEMBL23647755 | 0.61 | MOGAT2 (0.38) | MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090661-A1 | QUINOXALINE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |
| WO-2021144440-A1 | QUINOXALINE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR | Grünenthal GmbH (DE) | 2021-07-22 | — | — | WO | disclosed |