Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CBFB | Q13951 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599299 | 0.85 | BRD4 (0.46) | BRD4PDK2PDK4PDK1PDK3 | |
| SCHEMBL30559940 | 0.81 | AKR1B1 (0.43) | BRD4PDK2PDK4PDK1PDK3 | |
| SCHEMBL21624172 | 0.81 | AKR1B1 (0.43) | BRD4PDK2PDK4PDK1PDK3 | |
| SCHEMBL3595403 | 0.80 | BRD4 (0.36) | BRD4PDK2PDK4PDK1PDK3 | |
| SCHEMBL21624198 | 0.76 | ALOX5 (0.45) | BRD4GAAALDH1A1KDM4EMEN1 | |
| SCHEMBL21624183 | 0.76 | CES1 (0.45) | BRD4ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL30559951 | 0.76 | ALOX5 (0.45) | BRD4GAAALDH1A1KDM4EMEN1 | |
| SCHEMBL30559945 | 0.76 | CES1 (0.45) | BRD4ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL17817777 | 0.76 | ALOX5 (0.51) | BRD4GAAALDH1A1KDM4ELMNA | |
| SCHEMBL30132988 | 0.76 | ALOX5 (0.51) | BRD4GAAALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | BRD4 706/4885PDK2 3637/4885PDK4 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.