Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 8/20 | 0.36 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24767506 | 0.82 | MOGAT2 (0.39) | MOGAT2CYP2C19CES1ARTDP1 | |
| SCHEMBL23648159 | 0.70 | — | — | |
| SCHEMBL23648081 | 0.64 | AR (0.46) | MOGAT2CES1AR | |
| SCHEMBL30005426 | 0.63 | ALDH1A1 (0.34) | — | |
| SCHEMBL23648059 | 0.63 | ALDH1A1 (0.34) | — | |
| SCHEMBL23648061 | 0.63 | ALDH1A1 (0.34) | — | |
| SCHEMBL21072600 | 0.63 | CES1 (0.57) | CES1DAO | |
| SCHEMBL21624183 | 0.61 | CES1 (0.45) | MOGAT2CES1ARHSD11B1 | |
| SCHEMBL30559945 | 0.61 | CES1 (0.45) | MOGAT2CES1ARHSD11B1 | |
| SCHEMBL23647755 | 0.61 | MOGAT2 (0.38) | MOGAT2CES1ARDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021144439-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2021-07-22 | — | — | WO | disclosed |