Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23660879 | 0.83 | KDM4E (0.41) | ALDH1A1KDM4EHPGDATMTARBP2 | |
| SCHEMBL29054615 | 0.80 | KDM4E (0.48) | ALDH1A1KDM4EHPGDATMTARBP2 | |
| SCHEMBL29054666 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EHPGDATMTARBP2 | |
| SCHEMBL30507860 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EHPGDATMTARBP2 | |
| SCHEMBL29054603 | 0.74 | KDM4E (0.41) | ALDH1A1KDM4EHPGDTARBP2PKM | |
| SCHEMBL6852355 | 0.72 | TARBP2 (0.46) | ALDH1A1KDM4EHPGDATMTARBP2 | |
| SCHEMBL4489374 | 0.72 | KDM4E (0.43) | ALDH1A1KDM4EHPGDATMTARBP2 | |
| SCHEMBL9542161 | 0.72 | TARBP2 (0.50) | ALDH1A1KDM4EHPGDATMTARBP2 | |
| SCHEMBL30843235 | 0.72 | KDM4E (0.43) | ALDH1A1KDM4EHPGDATMTARBP2 | |
| SCHEMBL30507871 | 0.72 | KDM4E (0.53) | ALDH1A1KDM4EHPGDATMPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143822-A1 | BICYCLIC IMIDE DERIVATIVE, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2021-07-22 | — | — | WO | disclosed |