SCHEMBL23664347

SCHEMBL23664347

CCOCCOC(=O)C12CCCC1C(C)=NO2

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33
CHRM2 P08172 5/20 0.32
CHRM1 P11229 5/20 0.32
CYP3A4 P08684 3/20 0.32
LMNA P02545 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 2/20 0.32
SIGMAR1 Q99720 2/20 0.32
THRB P10828 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 1/20 0.32
SLC22A1 O15245 1/20 0.32
PRCP P42785 1/20 0.32
HTT P42858 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
LIPE Q05469 1/20 0.32
ABCB11 O95342 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23664310 0.90 KDM4E (0.35) TSHRALDH1A1CYP3A4LMNACYP1A2
SCHEMBL23664294 0.89 CYP3A4 (0.33) TSHRALDH1A1CHRM2CHRM1CYP3A4
SCHEMBL23664345 0.88
SCHEMBL23664352 0.88 HTT (0.31) HTT
SCHEMBL23664322 0.86 LMNA (0.35) TSHRALDH1A1CHRM2CHRM1CYP3A4
SCHEMBL23664568 0.86
SCHEMBL23664529 0.85
SCHEMBL23664299 0.85
SCHEMBL23664348 0.84 KMT2A (0.36) TSHRALDH1A1CYP3A4CYP1A2CYP2D6
SCHEMBL23664478 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021143677-A1 FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF 青岛清原化合物有限公司 2021-07-22 WO disclosed