Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17024326 | 0.80 | DHODH (0.41) | DHODHNPSR1ALDH1A1TSHRCASP1 | |
| SCHEMBL17024327 | 0.80 | DHODH (0.41) | DHODHNPSR1ALDH1A1TSHRCASP1 | |
| SCHEMBL217840 | 0.80 | DHODH (0.41) | DHODHNPSR1ALDH1A1TSHRCASP1 | |
| SCHEMBL12491707 | 0.80 | DHODH (0.41) | DHODHNPSR1ALDH1A1TSHRCASP1 | |
| SCHEMBL28247062 | 0.80 | DHODH (0.41) | DHODHNPSR1ALDH1A1TSHRCASP1 | |
| SCHEMBL5415654 | 0.80 | DHODH (0.41) | DHODHNPSR1ALDH1A1TSHRCASP1 | |
| SCHEMBL12491709 | 0.80 | DHODH (0.41) | DHODHNPSR1ALDH1A1TSHRCASP1 | |
| SCHEMBL1875182 | 0.79 | DHODH (0.44) | DHODHNPSR1PARP1PARP15PARP10 | |
| SCHEMBL17356892 | 0.77 | BRD4 (0.39) | ALDH1A1POLBPKMKDM4EMEN1 | |
| Bromide SCHEMBL689744 | 0.77 | DHODH (0.39) | DHODHNPSR1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143677-A1 | FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF | 青岛清原化合物有限公司 | 2021-07-22 | — | — | WO | disclosed |