SCHEMBL23664435

SCHEMBL23664435

Cc1ncc(C(F)(F)F)c(C)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MBOAT4 Q96T53 2/20 0.32
CYP1A2 P05177 2/20 0.31
LRRK2 Q5S007 2/20 0.31
AR P10275 1/20 0.31
PIK3CD O00329 1/20 0.31
NR3C1 P04150 1/20 0.31
ASPH Q12797 1/20 0.31
P2RX7 Q99572 1/20 0.31
COMT P21964 1/20 0.31
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6740290 0.83 PIK3CD (0.38) MBOAT4CYP1A2LRRK2ARPIK3CD
SCHEMBL20457080 0.81 TP53 (0.32)
SCHEMBL21606876 0.80 PIK3CD (0.36) MBOAT4ARPIK3CD
SCHEMBL6742485 0.80 COMT (0.35) CYP1A2LRRK2ARASPHP2RX7
SCHEMBL29930638 0.80 COMT (0.35) CYP1A2LRRK2ARASPHP2RX7
SCHEMBL28203352 0.80 MBOAT4 (0.39) MBOAT4PIK3CDCOMT
Hydrochloric Acid SCHEMBL27573305 0.79 PIK3CD (0.35) MBOAT4ARPIK3CD
SCHEMBL31214152 0.77 PIK3CD (0.39) MBOAT4CYP1A2LRRK2PIK3CDASPH
SCHEMBL3383488 0.76 KDM4E (0.38) MBOAT4CYP1A2LRRK2AR
SCHEMBL6899010 0.76 MBOAT4 (0.33) MBOAT4PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021143677-A1 FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF 青岛清原化合物有限公司 2021-07-22 WO disclosed