Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | MEN1 | O00255 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.55 |
| ▸ | NPC1 | O15118 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.50 |
| ▸ | RELA | Q04206 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23664473 | 0.81 | SMN1; SMN2 (0.49) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL13510513 | 0.80 | RAB9A (0.63) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL5027153 | 0.80 | NPC1 (0.70) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL12428584 | 0.79 | NPC1 (0.57) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL23664599 | 0.78 | PIK3CG (0.51) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL5025796 | 0.77 | MAPT (0.61) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL13766289 | 0.75 | SMN1; SMN2 (0.61) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL25322650 | 0.74 | SMN1; SMN2 (0.64) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL20694277 | 0.72 | GAA (0.47) | RAB9AMAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL13510374 | 0.72 | SMN1; SMN2 (0.61) | RAB9AMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145641-A1 | N-PHENOLBENZOTHIAZOL-2-AMINE COMPOUND HAVING ANTI-ANGIOGENETIC EFFECT, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 서울대학교산학협력단 | 2021-07-22 | — | — | WO | disclosed |