Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19253452 | 0.76 | SMN1; SMN2 (0.47) | ALDH1A1LMNASMN1; SMN2MAPK14MAPT | |
| SCHEMBL31277112 | 0.71 | KCNJ5 (0.50) | ALDH1A1 | |
| SCHEMBL19271750 | 0.69 | MAPK14 (0.47) | LMNASMN1; SMN2MAPK14MAPT | |
| SCHEMBL25833641 | 0.68 | — | — | |
| SCHEMBL11200266 | 0.67 | SMN1; SMN2 (0.62) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL24156506 | 0.67 | MAPK1 (0.37) | ALDH1A1LMNASMN1; SMN2MAPK14MAPT | |
| SCHEMBL6361845 | 0.64 | SMN1; SMN2 (0.62) | ALDH1A1LMNASMN1; SMN2MAPK14MAPT | |
| SCHEMBL26843192 | 0.64 | MEN1 (0.44) | ALDH1A1LMNAMAPTKDM4EHTT | |
| SCHEMBL1875633 | 0.62 | MMP2 (0.38) | ALDH1A1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL28404918 | 0.62 | KMT2A (0.68) | ALDH1A1LMNASMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021146192-A1 | SUBSTITUTED PYRAZOLO-PYRIMIDINES AND USES THEREOF | Verge Analytics, Inc. (US) | 2021-07-22 | — | — | WO | disclosed |