Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23666360 | 0.83 | SLC6A2 (0.40) | SLC6A2SLC6A4OPRM1CYP2D6HTR7 | |
| SCHEMBL23666359 | 0.83 | SLC6A2 (0.50) | SLC6A2SLC6A4OPRM1HTR7OPRD1 | |
| SCHEMBL23666378 | 0.83 | OPRM1 (0.42) | SLC6A2SLC6A4OPRM1HTR2CCYP2D6 | |
| SCHEMBL23666361 | 0.81 | OPRM1 (0.39) | SLC6A2SLC6A4OPRM1CYP2D6OPRD1 | |
| SCHEMBL23666363 | 0.81 | SLC6A2 (0.39) | SLC6A2SLC6A4HTR7OPRL1NPSR1 | |
| SCHEMBL23666362 | 0.80 | SLC6A2 (0.41) | SLC6A2SLC6A4OPRM1CYP2D6OPRD1 | |
| SCHEMBL23666366 | 0.72 | SLC6A2 (0.48) | SLC6A2SLC6A4OPRM1CYP2D6OPRD1 | |
| SCHEMBL12847350 | 0.71 | HTR2C (0.40) | SLC6A2SLC6A4OPRM1HTR2CGPR55 | |
| SCHEMBL23666381 | 0.68 | BCHE (0.43) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL23666379 | 0.68 | SLC6A2 (0.39) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145649-A1 | NOVEL N-HETEROCYCLIC CARBENE, TRANSITION METAL COMPLEX THEREOF, AND METHOD FOR PREPARING SAME | 포항공과대학교 산학협력단 | 2021-07-22 | — | — | WO | disclosed |