Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CDA | P32320 | 1/20 | 0.38 |
| ▸ | TK2 | O00142 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666288 | 0.88 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA | |
| SCHEMBL21980556 | 0.88 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA | |
| SCHEMBL30591063 | 0.87 | SLC28A1 (0.45) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA | |
| SCHEMBL18034249 | 0.84 | SLC28A1 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA | |
| SCHEMBL8402713 | 0.84 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA | |
| SCHEMBL8402712 | 0.84 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA | |
| SCHEMBL158124 | 0.84 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA | |
| SCHEMBL18512961 | 0.84 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA | |
| SCHEMBL14929312 | 0.84 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA | |
| SCHEMBL18574266 | 0.84 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021144475-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2021-07-22 | — | — | WO | disclosed |